But scientists have found that CBD doesn’t bind well with endocannabinoid receptors. Instead, CBD influences the system indirectly. This creates many benefits, which is why you’ll hear of CBD as a treatment for so many different medical conditions. And, unlike THC, it won’t make you high. When it comes to pain, we know that CBD has multiple functions. First, it influences neurotransmitters and receptors. One receptor known to be involved with pain and inflammation is called TRPV1 — also known as a vanilloid receptor. CBD binds to the TRPV1 receptor, influencing the way you perceive pain. CBD can also affect the production of neurotransmitters like serotonin and glutamate, which are related to pain sensation.

The science behind CBD is in the relatively early stages. As a cannabinoid, we know that CBD interacts with receptors in your endocannabinoid system. The endocannabinoid system is integrated throughout your body — and this widespread, whole-body interaction creates a broad range of effects. Hence, the long list of possible benefits.   We may still be in the early stages of discovery, but there’s plenty of scientific studies and anecdotal evidence that CBD provides relief for an array of ailments. Here’s a non-exhaustive list of some potential benefits of CBD oil:
Apply it by massaging the cream to the affected area. Use in small amounts first then reapply it if necessary. Some consumers claim that this cream works best in morning and in evening. You can apply this cream on your back, shoulders, knees or other affected area. The smell of this cream goes away quickly so you won’t be bothered if you don’t like its smell.

Customer Service: We’ve always received fast, informative responses to our queries about products and practices, but there are definitely customers out there who have not. A quick perusal of reviews shows customers who had issues with unaddressed orders. It’s hard to know exactly what the problem is in these situations, but the company’s strict return policy (seven days for unopened products only) probably doesn’t help. It should be noted that the company has a solid base of very satisfied customers as well.


I have severe psoriasis all over my body. It was suggested to me by several people to use CBD oil, CBD cream, or a CBD lotion. Can anyone recommend one they they have used personally for Psoriasis or Egsama that actually worked to clear up their plaques? I don’t have medical insurance and can’t afford the expensive prescriptions that are out there.
The interest and preference for botanical remedies such as CBD oil over harsh pharmaceuticals are growing rapidly. You can read scientific research on the promise of CBD Oil at NCBI. While North America is taking the lead legalizing cannabis and hemp the rest of the world is starting to question their stance on prohibition because of the undeniable benefits. While all talk about plant-based remedies may seem very new, using cannabis/hemp tinctures as a holistic remedy is a generations-old tradition. It was very common to use tinctures of cannabis oil in the eighteenth and nineteenth centuries. We are enjoying a renaissance in ancestral health where we are open again to remedies that were all but forgotten about in the mad race to make medicines a pill offered by a faceless often unaccountable corporation.
Transparency: Receptra Naturals’ website has a database where you can look up lab reports for their products. The first time we checked, we got some 404 errors for a couple of the lab reports, but these glitches seem to have been fixed since then. We were able to see third-party lab reports for all their tinctures (though, apparently not for their topicals).  

Customer Service: There are multiple ways to get in touch with customer service, and Pure Hemp Botanicals’ customer service representatives are both quick to respond and forthcoming with information. On the down side, free shipping kicks in at $100 — otherwise it’s a pricey $9.99 flat rate. And you can return products, but only if they’re unopened.
The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product.
Customer Service: It’s difficult to find contact information on Calm by Wellness’s website, and their email address is listed incorrectly in two places (we tried sending them an email but it was not delivered). We were, however, able to get a response through Facebook, and the company does offer free shipping and a generous 30-day return policy on all orders.
CBD is suddenly everywhere — and it’s not hard to see why. It won’t get you high, has a good safety profile, and naturally treats dozens of conditions. But there’s a dizzying amount of choice out there, so we’ve ranked the 25 best CBD oils to help you get started.  Whether you’re a rank beginner, or you’ve been experimenting with CBD for a while, we’ve got you covered. 
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